5-Aminovaleric acid
CAS No. 660-88-8
5-Aminovaleric acid ( —— )
Catalog No. M19658 CAS No. 660-88-8
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
500MG | 56 | In Stock |
|
1G | 78 | In Stock |
|
Biological Information
-
Product Name5-Aminovaleric acid
-
NoteResearch use only not for human use.
-
Brief Description5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine.
-
Description5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction: L-lysine leads to cadverine leads to L-piperideine leads 5-aminovalerate . In other words it is a metabolite of cadaverine which is formed via the intermediate 1-piperideine. Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue. High levels of 5-aminovalerate in biofluids may indicate bacterial overgrowth or endogenous tissue necrosis. In most cases endogenous 5-aminovalerate is thought to be primarily a microbial metabolite produced by the gut or oral microflora although it can be produced endogenously. 5-aminopentanoic acid is an in vivo substrate of 4-aminobutyrate:2-oxoglutarate aminotransferase .
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
Recptorothers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number660-88-8
-
Formula Weight117.15
-
Molecular FormulaC5H11NO2
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESNCCCCC(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Santos A Zanetta S Cresteil T et al. Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans[J]. Clinical Cancer Research 2000 6(5):2012-2020.
molnova catalog
related products
-
Oleoylethanolamide
Oleoylethanolamide is a high affinity endogenous agonist of PPAR-α.In vitro studies showed that OEA inhibited transforming growth factor β1-stimulated HSCs activation through suppressing Smad2/3 phosphorylation, α-SMA expression and myofibroblast transformation.
-
N-Acetylputrescine h...
N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine.
-
D-Cysteine
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli.